TABLE 4.

Outcomes in patients with Wilson's disease by decade

	Hazard ratio (95% CI) by decade
	Time to death	Time to death or dependence	Time to death or liver transplant
<1959	1.84 (0.82–4.13)	1.44 (0.53–3.90)	0.91 (0.42–1.97)
1960–1969	2.49 (1.42–4.37)	1.59 (0.80–3.15)	1.23 (0.74–2.04)
1970–1979	3.23 (1.95–5.34)	2.66 (1.52–4.67)	1.60 (1.03–2.48)
1980–1989	1.85 (1.03–3.35)	1.37 (0.69–2.71)	0.98 (0.58–1.67)
1990–1999	2.03 (1.26–3.28)	1.57 (0.95–2.61)	1.06 (0.71–1.58)
2000–2009	Reference	Reference	Reference
2010–2019	1.19 (0.64–2.21)	1.83 (1.02–3.29)	0.74 (0.45–1.22)

Abbreviation: CI, confidence interval.