Fig. 5.

TBN decreases oxidative damage products in SN of MPTP-induced mice. (A) Representative photomicrographs of immunofluorescence staining for 8-OHdG (green), 4-HNE (green), TH (red), 3-NT (green), and Hoechst 33,342 (blue) from SN of MPTP mice. Scale bars, 20 μm. (B-D) Fluorescence intensity of 8-OHdG, 4-HNE, and 3-NT in the SN. Data are mean ± SD of 3 mice per group. Three amplifying fields in each section were randomly chosen to conduct a semi-quantitative analysis. Data were analyzed using one-way ANOVA followed by Dunnett’s multiple comparisons test. ^***P < 0.001 versus sham group; ^#P < 0.05 and ^###P < 0.001 versus MPTP group. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)