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TBN regulates AKT/GSK3β and CDK5 protein expression in MPTP-induced mice PD model. (A, B) Western blot showed that TBN increased phosphorylated AKT (Ser 473) and phosphorylated GSK3β (Ser 9), and decreased the expression of CKD5, as compared with the MPTP model group. Data are mean ± SD of 4 mice per group. Data were analyzed using one-way ANOVA followed by Dunnett’s multiple comparisons test. **P < 0.01 versus sham group; #P < 0.05 and ##P < 0.01 versus MPTP group.
