Table 2.
The roles of ferroptosis in the diagnosis of urological malignancies.
| Cancers | Target | Relationship with ferroptosis | Biological function | Reference |
|---|---|---|---|---|
| RCC | CCR4,NR3C2 | Ferroptosis and immune-related differentially expressed genes | Better OS | [84] |
| CMTM3, IFITM1 and MX2 | Ferroptosis and immune-related differentially expressed genes | Worse OS | [84] | |
| CRFGs | Cuproptosis-related Ferroptosis genes | Worse OS | [85] | |
| CBS、CD44、AKR1C2、CHAC1 and SLC7A11 | Ferroptosis-related gene | Worse OS | [86] | |
| HMOX1 and HMGCR | Ferroptosis-related gene | Better OS | [86] | |
| SLC7A11 | Ferroptosis-related gene | Worse OS | [89] | |
| PCa | ARPC1A | Inhibit | Worse DFS | [93] |
| E2F1, CDC20, TYMS,and NUP85 | Ferroptosis-related gene prognostic index | Worse DFS | [94] | |
| five frlncRNAs | Ferroptosis-related lncRNA | Higher disease grades and a greater number of infiltrating immune cells | [95] |