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. 2024 Oct 9;15(10):734. doi: 10.1038/s41419-024-07089-4

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A The correlation between DTL and cellular response to the hypoxia pathway was analyzed with Spearman. B Representative IHC staining of HIF-1α, DTL, and N-cadherin in DTL-high and DTL-low HCC tissue. C Correlation analysis between the IHC score of DTL and HIF-1α (n = 209). D The mRNA levels of DTL at different hypoxia time points. E Protein expression of DTL and HIF-1α at different time points. *P < 0.05, ***P < 0.001, ns no significance.