Table 4.

Survival analyses for prognosticators of survival in recurrence epithelioid glioblastoma

Parameter	Univariate				Multivariate
	HR	95% Confidence Interval	P	HR	95% Confidence Interval	P
Age	0.989	0.958–1.021	0.495
Sex	2.451	1.011–5.939	0.047	3.010	0.993–9.127	0.052
Recurrent-KPS	0.967	0.929–1.007	0.103	1.007	0.964–1.053	0.744
Bevacizumab	1.021	0.414–2.517	0.964
Reoperation	0.116	0.03634–0.371	< 0.001	0.179	0.053–0.611	0.006
Re-irradiation	0.542	0.220–1.337	0.183	0.494	0.177–1.380	0.179
Ki-67	0.934	0.364–2.395	0.888
BRAF inhibitor	1.180	0.397–3.506	0.766
BRAF-V600E	1.259	0.539–2.940	0.594
MGMT	2.111	0.861–5.180	0.103	2.571	0.767–8.618	0.126
ATRX	1.625	0.541–4.876	0.387
GFAP	0.285	0.035–2.324	0.241
Olig-2	0.744	0.217–2.546	0.634
P53	1154	0.464–2.871	0.757

KPS Karnofsky Performance Scale, MGMT Methylguanine DNA Methyltransferase, GFAP Glial Fibrillary Acidic Protein, ATRX X-linked alpha-thalassemia mental retardation syndrome, Olig-2 Oligodendrocyte Transcription Factor 2