Figure 3.

Extended flanking haplotype plot around k13 Arg561His mutations

Every SNP, insertion or deletion passing filters between 1 707 537 bp and 1 752 231 on chromosome 13 is presented as a coloured line, the SNP coding for pure mutant Arg561His is shown in red. All samples were jointly called for variation. Grey regions represent loci where a call could not be made due to low coverage. The top panel represents wild-type and mixed genotypes at position 561. The middle panel shows a common haplotype between Rwandan and Tanzanian isolates. The bottom panel shows a novel haplotype flanking Arg561His detected in Kagera. SNP=single-nucleotide polymorphism.