Figure 5.
Effects of propofol on cell apoptosis and cell cycle progression. (A) Flow cytometric plots were generated to assess the expression of Annexin V-FITC and PI on 4T1 cell following 24 h treatment with propofol. Quadrants were set based on controls to distinguish positive and negative populations. The histogram displays the quantification of cells in each population. (B) Flow cytometric analysis of 4T1 cells revealed the distribution of cells G1, S and G2/M phases following 24 h treatment with propofol. The histogram illustrates the relative proportions of cells in each cell cycle phase. Data are presented as the mean ± SD (n=4). Ctrl, control.