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. Author manuscript; available in PMC: 2024 Oct 10.
Published in final edited form as: Nat Genet. 2024 Jun 17;56(7):1386–1396. doi: 10.1038/s41588-024-01792-w

Extended Data Fig. 9 |. Contribution of PGS to inter-individual variation of prediction SDs in All of Us.

Extended Data Fig. 9 |

We compared inter-individual variation of prediction SDs in two models: (1) prediction mean as a function of all contexts without PGS; (2) include PGS as part of prediction mean in the baseline model. Prediction SD is modeled as a function of all contexts in both models. By comparing prediction SDs in these two models, we found including PGS substantially impacted inter-individual variation in prediction SD.