FIG. 5.

Addition of IL-12 enhances NK-mediated cytotoxicity in RSV-infected TLR4^null mice. BAL samples from TLR4^null and TLR4^wt mice were examined for cytotoxicity 7 days post-RSV infection. Effector BAL cells were cultured in the presence of 2 ng of IL-12/ml for 24 h. NK lytic activities against YAC-1 target cells at effector-to-target ratios of 40:1 (presented), 20:1, 10:1, and 5:1 (data not shown) were analyzed. A representative experiment is shown.