Table 3.
Association of Sarcopenia status and IR surrogate indicators with new onset of stroke
| Group | Case | Incidence rate (per1000 person-year) | Model 1 HR (95%CI) | Model 2 HR (95%CI) | Model 3 HR (95%CI) |
|---|---|---|---|---|---|
| Non-sarcopenia & Low TyG | 104 | 6.89 | 1.00(Reference) | ||
| Possible sarcopenia and sarcopenia & Low TyG | 95 | 10.84 | 1.59(1.20,2.10)** | 1.40 (1.05,1.86)* | 1.30 (0.97,1.73) |
| Non-sarcopenia & High TyG | 150 | 9.77 | 1.43(1.11,1.83)** | 1.46 (1.13,1.87)** | 1.16 (0.90,1.50) |
| Possible sarcopenia and sarcopenia & High TyG | 166 | 18.13 | 2.70(2.11,3.45)*** | 2.44(1.89,3.16)*** | 1.82(1.40,2.37)*** |
| Non-sarcopenia & Low TyG-BMI | 90 | 6.02 | 1.00(Reference) | ||
| Possible sarcopenia and sarcopenia & Low TyG-BMI | 110 | 11.84 | 2.00(1.51,2.64)*** | 1.70(1.27,2.26)*** | 1.63 (1.22,2.17)** |
| Non-sarcopenia & High TyG-BMI | 164 | 10.58 | 1.78(1.37,2.30)*** | 1.92(1.48,2.49)*** | 1.37 (1.05,1.79)** |
| Possible sarcopenia and sarcopenia & High TyG-BMI | 151 | 17.49 | 2.98(2.30,3.87)*** | 2.86(2.19,3.75)*** | 1.86(1.41,2.47)*** |
| Non-sarcopenia & Low TyG-WC | 81 | 5.26 | 1.00(Reference) | ||
| Possible sarcopenia and sarcopenia & Low TyG-WC | 106 | 11.93 | 2.31(1.73,3.08)*** | 2.00(1.49,2.70)*** | 1.90(1.41,2.55)*** |
| Non-sarcopenia & High TyG-WC | 173 | 11.49 | 2.22(1.70,2.88)*** | 2.24(1.72,2.92)*** | 1.62 (1.23,2.12)** |
| Possible sarcopenia and sarcopenia & High TyG-WC | 155 | 17.12 | 3.34(2.55,4.37)*** | 3.03(2.29,4.00)*** | 2.03(1.52,2.70)*** |
| Non-sarcopenia & Low TyG-WHtR | 95 | 6.02 | 1.00(Reference) | ||
| Possible sarcopenia and sarcopenia & Low TyG-WHtR | 91 | 10.86 | 1.83(1.37,2.44)*** | 1.63 (1.21,2.18)** | 1.56 (1.16,2.10)** |
| Non-sarcopenia & High TyG-WHtR | 159 | 10.83 | 1.82(1.41,2.35)*** | 1.94(1.50,2.51)*** | 1.42 (1.09,1.85)** |
| Possible sarcopenia and sarcopenia & High TyG-WHtR | 170 | 17.77 | 3.03(2.36,3.90)*** | 2.92(2.24,3.82)*** | 1.98(1.51,2.62)*** |
| Non-sarcopenia & Low TG/HDL-C | 103 | 6.81 | 1.00(Reference) | ||
| Possible sarcopenia and sarcopenia & Low TG/HDL-C | 97 | 10.77 | 1.60 (1.21,2.11)** | 1.38 (1.04,1.84)* | 1.28 (0.96,1.71) |
| Non-sarcopenia & High TG/HDL-C | 151 | 9.84 | 1.46 (1.13,1.87)** | 1.48 (1.16,1.91)** | 1.20 (0.93,1.55) |
| Possible sarcopenia and sarcopenia & High TG/HDL-C | 164 | 18.40 | 2.77(2.17,3.55)*** | 2.51(1.94,3.23)*** | 1.90(1.47,2.47)*** |
| Non-sarcopenia & Low METS-IR | 87 | 5.83 | 1.00(Reference) | ||
| Possible sarcopenia and sarcopenia & Low METS-IR | 113 | 12.11 | 2.11(1.59,2.79)*** | 1.79(1.34,2.39)*** | 1.70(1.27,2.27)*** |
| Non-sarcopenia & High METS-IR | 167 | 10.75 | 1.87(1.44,2.42)*** | 1.98(1.52,2.56)*** | 1.44 (1.10,1.88)** |
| Possible sarcopenia and sarcopenia & High METS-IR | 148 | 17.23 | 3.03(2.33,3.95)*** | 2.85(2.18,3.74)*** | 1.91(1.44,2.53)*** |
Model 1: unadjusted; Model 2: adjusted for age, sex; Model 3: adjusted as model 2 with further adjustment for systolic, diastolic, smoking, drinking, hypertension, diabetes, heart disease, dyslipidemia, hypertension medications, diabetes medications, dyslipidemia medications
*P < 0.05, **P < 0.01, *** P < 0.001; IR surrogate category: divide into high value and low value groups based on the median