Table 4. Multivariate binary logistic regression analysis of predictors of metabolic syndrome in patients with schizophrenia, Ethiopia (N = 271).
*p < 0.05
AOR: Adjusted odds ratio; BMI: Body mass index; CPZ: Chlorpromazine; COR: Crude odds ratio; SD: Standard deviation; DUP: Duration of untreated psychosis; PANSS: Positive and negative syndrome scale
| Variables | Without MetS | With MetS | COR (95% CI) | AOR (95% CI) |
| Gender | ||||
| Male | 163 (66.8) | 81 (33.2) | 1 | 1 |
| Female | 11 (40.7) | 16 (59.3) | 2.9 (1.3, 2.6) | 3 (1.2, 7.4)* |
| Employment status | ||||
| Employed | 70 (59.3) | 48 (40.7) | 1 | 1 |
| Unemployed | 104 (68) | 49 (32) | 0.67 (0.4, 1.1) | 0.7 (0.4, 1.1) |
| Substance use | ||||
| Yes | 76 (59.8) | 51 (40.2) | 1 | 1 |
| No | 98 (68.1) | 46 (31.9) | 0.7 (0.4, 1.2) | 0.6 (0.3, 1.0) |
| BMI | ||||
| <25 | 150 (66.1) | 77 (33.9) | 1 | 1 |
| ≥25 | 24 (54.5) | 20 (45.5) | 1.6 (0.8, 3.1) | 1.4 (0.7, 2.9) |
| Medication type | ||||
| Risperidone | 112 (72.3) | 43 (27.7) | 1 | 1 |
| Olanzapine | 62 (53.4) | 54 (46.6) | 2.3 (1.4, 3.8) | 2.2 (1.3, 3.7)* |
| Medication switch | ||||
| Yes | 88 (59.5) | 60 (40.5) | 1 | 1 |
| No | 86 (69.9) | 37 (30.1) | 0.6 (0.4, 1.1) | 0.6 (0.4, 1.1) |
| PANSS total score (mean, SD) | 68.6 (35.7) | 75.5 (36) | 1.01 (0.9, 1.0) | 1 (0.9, 1.0) |
| DUP (years) | ||||
| <1 | 116 (61.1) | 74 (38.9) | 1 | 1 |
| ≥1 | 58 (71.6) | 23 (28.4) | 0.6 (0.4, 1.1) | 0.6 (0.3, 1.1) |