Figure 3.

The sensitivity analyses indicate no bias. The leave-one-out sensitivity analyses are portrayed in the forest plots. (A) Causal estimates in the first MR analysis (setting GCST007725 as exposure and ukb-e-208_CSA as the outcome). (B) Causal estimates in the second MR analysis (setting ukb-e-30880_CSA as exposure and ukb-e-208_CSA as the outcome). Each black dot indicates the calculated causal effect size employing all SNPs, except for the SNP indicated on the y axis. The red dot symbolizes IVW estimates incorporating all SNPs. Error bars represent the 95% CI in each MR analysis. CI = confidence interval, IVW = inverse variance-weighted, MR = Mendelian randomization, SNP = single nucleotide polymorphism.