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Replication of viruses in hPrMC. Crude 4-week-old hPrMC were infected with the M-tropic HIV-1 strain NL4-3-ADA and the T-tropic strain NL4-3-HXBc2. The RT inhibitor AZT was used on ADA-infected hPrMC at a concentration of 50 μM. Culture supernatants were harvested on the days indicated and assayed for p24gag concentration. Similar results were obtained in two independent experiments; the results for one experiment are shown.
