Table 4. Description of HLA alleles or allele groups known to be associated with VL development on other continents.
Alleles are described as protective against VL development (OR < 1) or as increasing the risk for VL development (OR > 1). This table was taken and adapted from de Vrij et al., 2021 [15].
| Reference | Protective alleles | Risk alleles | Sample size | Species | Study Location |
|---|---|---|---|---|---|
| Singh et al., 2018 [17] | DRB1*01:01 DRB1*15:01 DRB1*15:02 DRB1*16:02 |
DRB1*11 DRB1*14:04 DRB1*13:01 DRB1*13:02 |
Patients N = 889
Control N = 977 |
L. donovani L. infantum |
India Brazil |
| Fakiola et al., 2013 [16] | DRB1*01 DRB1*15 DRB1*16 |
DRB1*11 DRB1*13 DRB1*14 |
Three cohorts. Total Patients N = 2287 Total Control N = 3692 |
L. donovani L. infantum |
India Brazil |
| Faghiri et al., 1995 [18] | A*26 |
Patients N = 52
Control N = 222 |
L. donovani | Iran |