Fig. 3.

Parameters of thrombus formation, Occlusion Time (Panel A) and area under the curve (AUC) (Panel B), in AT children (n = 27), individuals with heterozygous mutation of ATM (h-ATM) gene (n = 29), children (AT Controls n = 27) and adult controls (h-ATM Controls n = 29). Data are expressed as mean values ± standard deviation (SD), and ∗p < 0.01.

Representative picture of thrombus formation (Panel C) in AT children, individuals with heterozygous mutation of ATM (h-ATM) gene, children, and adult controls. Blood flow direction is from right to left (see arrow). The width and depth of the capillaries are both 40 μm.