Figure 1.

Comparison of expression levels of EGFP by injection of nine different serotype AAV vectors into the marmoset cortex

(A) Schema depicting injection of AAV vectors into a marmoset. Nine AAV capsid vectors expressing EGFP under the control of the CBh promoter were injected into the marmoset cerebral cortex. (B) The coordinate of the viral injection with reference to the bregma of the marmoset skull. (C) Example of EGFP fluorescence image of marmoset cortex 4 weeks after viral injection. The lower left inset is a bright-field brain image of a marmoset (animal ID: H257, see Table 1). Scale bar, 10 mm. (D) Graph showing the diameter of EGFP fluorescence on the cortex. Error bars indicate SEM, and dots in the graph indicate the respective values for each of the individual marmosets. No statistically significant differences were observed in the EGFP fluorescence diameters by a Kruskal-Wallis test with Dunn’s post hoc test. n.s., not significant.