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Alterations of mineral metabolism over time. Measurements of T50 (A, n= 54, Wilcoxon matched pair signed rank test) and CPP2 size (hydrodynamic radius, B, n= 54, Wilcoxon matched pair signed rank test) as well as phosphate (C, n= 46, paired t-test), 1-84 PTH (D, n=50, Wilcoxon matched pair signed rank test) and iFGF23 (E, n=51, Wilcoxon matched pair signed rank test) in patients with SSc at baseline and at follow-up. *** indicates p<0.001.
