Table 2.

Association between the LE8 score and low thyroid function.

	Model 1a		Model 2b		Model 3c
	OR(95% CI)	P-value	OR(95% CI)	P-value	OR(95% CI)	P-value
LE8 score
Low (0-49)	1.000 (Reference)		1.000 (Reference)		1.000 (Reference)
Moderate (50-79)	0.874 (0.744, 1.026)	0.09885	0.862 (0.732, 1.016)	0.07696	0.856 (0.725, 1.011)	0.06705
High (80-100)	0.763 (0.620, 0.938)	0.01037	0.767 (0.619, 0.950)	0.01496	0.757 (0.607, 0.944)	0.01341
Per 10-point increase	0.932 (0.895, 0.969)	0.00049	0.928 (0.890, 0.968)	0.00044	0.923 (0.884, 0.964)	0.00030
Health behaviors score
Low (0-49)	1.000 (Reference)		1.000 (Reference)		1.000 (Reference)
Moderate (50-79)	1.092 (0.939, 1.271)	0.25158	1.049 (0.900, 1.224)	0.53907	1.047 (0.896, 1.223)	0.56591
High (80-100)	1.108 (0.938, 1.310)	0.22837	1.004 (0.846, 1.191)	0.96340	1.003 (0.841, 1.197)	0.97102
Per 10-point increase	1.028 (0.998, 1.058)	0.06834	1.008 (0.979, 1.039)	0.58871	1.009 (0.978, 1.041)	0.56742
Health factors score
Low (0-49)	1.000 (Reference)		1.000 (Reference)		1.000 (Reference)
Moderate (50-79)	0.794 (0.686, 0.918)	0.00181	0.789 (0.680, 0.916)	0.00186	0.789 (0.680, 0.917)	0.00196
High (80-100)	0.533 (0.448, 0.634)	<0.00001	0.578 (0.482, 0.693)	<0.00001	0.572 (0.475, 0.688)	<0.00001
Per 10-point increase	0.897 (0.871, 0.925)	<0.00001	0.907 (0.879, 0.937)	<0.00001	0.905 (0.876, 0.935)	<0.00001

^aModel 1: no covariates were adjusted.

^bModel 2: age strata, sex, and race/ethnicity were adjusted.

^cModel 3: age strata, sex, race/ethnicity, education level, marital status, and UIC.

LE8, Life’s Essential 8; UIC, urine iodine concentration; OR, odds ratio; CI, confidence interval.