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. 2024 Sep 27;15:1436194. doi: 10.3389/fgene.2024.1436194

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Copyright © 2024 Bezstarosti, Erpicum, Maggipinto, Dreyer, Reinders, Meziyerh, Roelen, De Fijter, Kers, Weekers, Beguin, Jouret and Heidt.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Solvent-accessible amino acid mismatches of DQB1 between the recipient, kidney donor, and MSC donor. (A) DQB1 typing of Neptune patient #10 showed no repeated antigen mismatches but 14 repeated amino acid mismatches. (B) DQB1 typing of Liège patient #6 showed a single repeated antigen mismatch (DQ6) and two corresponding repeated amino acid mismatches. Color legend: green, typing of the recipient; blue, mismatches between the recipient and kidney donor; yellow, mismatches between the recipient and MSC donor; red, repeated mismatches. MSC, mesenchymal stromal cell.