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. 2024 Oct 10;11:1111. doi: 10.1038/s41597-024-03965-y

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Overview of the total proteomics data. (A) Number of proteins identified in each sample (n = 215). To note, one of the technical replicates for the untreated NLF/NTRK1 total proteomics sample was removed after preprocessing and normalisation due to low number of proteins identified by MS. (B) Principal component analysis (PCA) of the samples (C) Number of differently expressed proteins in each sample at each time point (adjusted p-value < 0.05, absolute fold change > 1 from unstimulated cells).