TABLE 1.
C-terminal mutations in LMP2A
| Wild type or mutant | C-terminal sequence |
|---|---|
| WT CTa | RCCRYCCYYCLTLESEERPPTPYRNTV |
| T496A | RCCRYCCYYCLTLESEERPPTPYRNAV |
| T496E | RCCRYCCYYCLTLESEERPPTPYRNEV |
| E6 Ter | RCCRYCCYYCLTLESEERPPTPYRETQV |
| Y493F | RCCRYCCYYCLTLESEERPPTPFRNTV |
| Δ NTV | RCCRYCCYYCLTLESEERPPTPYR |
| KMN CT | RCCRYCCYYCLTLESEERPPTPYRKMN |
| SEI CT | RCCRYCCYYCLTLESEERPPTPYRSEI |
| Δ Cysb | KRKKQRSRRNLTLESEERPPTPYRNTV |
a
WT, wild type.
b
In the Δ Cys mutation, the cysteine-rich membrane anchor sequence was replaced with the corresponding sequence from the CD2 membrane protein (indicated in boldface).