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Bioavailability radar of (a) favipiravir F, (b) L4, (c) L6, and (d) L7. The pink area represents the optimal range for each property (solubility: log S not higher than 6, lipophilicity: XLOGP3 between −0.7 and + 5.0, saturation: fraction of carbons in the sp3 hybridization not less than 0.25, size: TPSA between 20 and 130Å2, and flexibility: no more than 9 rotatable bonds.
