TABLE 4.
Presence of the putative Mamu-DRB peptide binding motif in SIV-derived overlapping 15-mer peptides
| SIV-derived overlapping 15-mer peptides | Mamu-DR motif-positive peptidesa
|
|
|---|---|---|
| Mamu-DRB1*0406 | Mamu-DRB*w201 | |
| Good binders (1–100 nM) | 5/6 (83) | 9/12 (75) |
| Intermediate binders (101–1,000 nM) | 12/22 (54) | 25/41 (56) |
| Nonbinders (>1,000 nM) | 85/283 (30) | 68/258 (26) |
| Total | 102/311 (33) | 102/311 (33) |
a
The number of Mamu-DR motif-positive peptides to the total number of peptides is shown, with the percentage indicated in parentheses. The values for the good binders were statistically significantly different from the values for the intermediate binders and nonbinders (P = 0.00000008).