FIGURE 4.

LTF induced functional alterations in endplate chondrocytes, suppressed the JAK2/STAT3 pathway, and reversed the impact of si‐LTF treatment. (A–D) IF staining of LTF, Runx2, P21, and MMP13 in a human chondrocyte (Scale bar = 100 μm). (E) SA‐β‐gal staining and quantification of positive cells as a proportion of total cells in the three groups (Scale bar = 100 μm). (F) Von Kossa staining and quantification of nodules in the three groups (Scale bar = 100 μm) (Scale bar = 100 μm). All data are presented as mean ± SD (n = 3); *p < 0.05, **p < 0.01.