Table 3.
Univariate and multivariate analyses of predictors of death for 240 patients with idiopathic interstitial pneumonia
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Hazard ratio | 95% confidence interval | P-value | Hazard ratio | 95% confidence interval | P-value | |
| Sex (male) | 2.004 | 0.869–4.620 | 0.103 | 2.882 | 0.981–8.475 | 0.054 |
| Age at initial visit | 1.070 | 1.017–1.126 | 0.009 | 1.072 | 1.017–1.131 | 0.01 |
| Smoking history (BI > 100) | 1.080 | 0.537–2.171 | 0.830 | 0.604 | 0.239–1.529 | 0.287 |
| ILD pattern (UIP) | 1.593 | 0.797–3.188 | 0.188 | 2.049 | 0.921–4.566 | 0.079 |
| Jo-1 | 0.049 | 0 | 0.875 | 0.000 | 0 | 0.995 |
| EJ | 0.048 | 0–41,337 | 0.664 | 0.000 | 0 | 0.982 |
| OJ | 2.466 | 0.588–10.335 | 0.217 | 1.919 | 0.402–9.174 | 0.414 |
| PL-7 | 2.636 | 1.015–6.847 | 0.047 | 4.785 | 1.528–14.925 | 0.007 |
| PL-12 | 4.435 | 1.552–12.675 | 0.005 | 3.922 | 1.198–12.821 | 0.024 |
| SRP | 1.389 | 0.332–5.821 | 0.653 | 1.425 | 0.314–6.452 | 0.647 |
| Mi-2 | 0.763 | 0.104–5.591 | 0.790 | 1.082 | 0.141–8.264 | 0.939 |
BI, Brinkman Index; ILD, interstitial lung disease; UIP, usual interstitial pneumonia
Multivariate analysis was performed using models with variables selected a priori (sex and age at the initial visit, smoking history with Brinkman Index > 100), ILD pattern with UIP, MSA (Jo-1, EJ, OJ, PL-7, PL-12, SRP, and Mi-2). Bold values are statistically significant (P < 0.05)