Figure 2.

Biofabrication of organotypic full‐thickness gingival equivalents underflow and static conditions. A) Schematic representation of the organotypic culture under flow within the microfluidic device (gingiva‐on‐chip) and under static conditions using porous culture inserts (gingiva‐insert). The culture under both conditions includes mucosal matrix fabrication, keratinocyte seeding, and air‐liquid interface culture followed by their downstream applications. Macroscopic views of the gingival tissues fabricated within the B) microfluidic device and C) in static insert culture systems. The gingiva‐on‐chip equivalents within the microfluidic device B) are visible and easily accessible through the lid opening in the upper chamber (inset).