Figure 7.

Gene silencing activity in different cell types treated with liposomes and hybrid nanoparticles encapsulating siRNA. Different cell types were incubated with liposomes and hybrids at concentrations ranging from 0.1 to 50 nm siRNA and gene‐silencing was analyzed after 48 h by measurement of luciferase expression. Data are plotted as the normalized ratio of firefly to renilla luciferase expression. A) SKOV3‐dluc. B) HEK293T‐dluc. C) U87‐MG‐dluc. Data are representative of three independent experiments and expressed as mean ± SD (n = 3, technical replicates), one‐way ANOVA with Tukey's post‐hoc test, ^* p < 0.05, ^** p < 0.01, and ^*** p < 0.001.