Table 6.
Associations between NOVA intake (in g /d) and breast cancer risk, stratified by alcohol intake and BMI at recruitment
| Characteristics at recruitment | NOVA 1 | NOVA 2 | NOVA 3 | NOVA 4 | |
|---|---|---|---|---|---|
|
N cases |
HR per 1 SD (95%CI)a | HR per 1 SD (95%CI)a | HR per 1 SD (95%CI)a | HR per 1 SD (95%CI)a | |
| Alcohol intake (g/d) | |||||
| Non-drinkers | 2014 | 0.99 (0.93-1.05) | 1.00 (0.94-1.05) | 1.00 (0.91-1.10) | 1.01 (0.95-1.07) |
| > 0 - ≤3 | 4311 | 0.97(0.93-1.01) | 1.03 (0.99-1.07) | 1.00 (0.93-1.07) | 1.01 (0.98-1.05) |
| >3 - ≤12 | 4594 | 1.02 (0.98-1.06) | 1.02 (0.98-1.06) | 0.99 (0.93-1.05) | 1.00 (0.97-1.04) |
| >12 - ≤24 | 2298 | 0.98 (0.93-1.03) | 0.97 (0.92-1.03) | 1.05 (0.99-1.12) | 1.01 (0.96-1.07) |
| >24 | 1716 | 0.99 (0.93-1.05) | 0.99 (0.93-1.05) | 1.02 (0.99-1.06) | 1.01(0.95-1.07) |
| Pinteraction | 0.79 | 0.17 | 0.68 | 0.52 | |
| Body mass index | |||||
| <25 | 8871 | 0.99 (0.97-1.02) | 1.01 (0.98-1.04) | 1.05 (1.03-1.08) | 1.01 (0.98-1.04) |
| ≥25 | 6062 | 0.97 (0.94-1.01) | 1.01 (0.97-1.04) | 1.05 (1.02-1.08) | 1.00 (0.97-1.03) |
| Pinteraction | 0.57 | 0.31 | 0.27 | 0.88 | |
CI Confidence Interval, NOVA 1 Unprocessed/minimally processed foods, NOVA 2 Processed culinary ingredients, NOVA 3 Processed foods, NOVA 4 Ultra-processed foods, SD Standard deviation
aModels were stratified by age and center and adjusted for education, height, physical activity, age at menarche, oral contraceptive use, age at first full-term pregnancy, parity, breastfeeding, menopausal status and menopausal hormone therapy use. Each NOVA group was mutually adjusted for the other NOVA groups