Table 1.
Compositional parameter space of the developed AP platform
| Backbone | MWbb a) [kDa] | MA b) [%] | PEG/S c) | MWPEG d) [kDa] | AM e) | CI f) |
|---|---|---|---|---|---|---|
| 1 | 10 | 10 | 3–58 | 2, 5, 10, 20 | — | — |
| 2 | 10 | 30 | 8–165 | 2, 5, 10, 20 | HEX | PEP/HEP |
| 3 | 80 | 30 | 6–32 | 2, 5 | — | — |
| 4 | 120 | 30 | 6–33 | 2, 5 | — | — |
| 5 | 350 | 50 | 22–470 | 2, 5, 10, 20 | HEX | PEP |
a)
Molecular weight of polymer backbone
b)
Maleic acid content of polymer backbone, styrene content (S): 100 – MA
c)
Ratio PEG to styrene units
d)
Molecular weight of the PEG chain
e)
Antimicrobial bioactive: hexetidine (HEX)
f)
Cell‐instructive bioactives: peptides (PEP): CRGDSP, CIKVAV, CEIDGIELT, CSIRT or heparin (HEP); see also Table S3, Supporting Information, for detailed information.