Table 3.
Antiseptic effect of Ag NPs on kidney oxidative stress biomarkers of septic mice
Parameters | Groups | ||
---|---|---|---|
Sepsis | |||
Control | Vehicle | Ag NPs | |
GSH (mM/g.tissue) |
1.76 ± 0.08 a | 0.72 ± 0.05 b | 1.23 ± 0.07 c |
SOD (U/g.tissue) |
195.81 ± 5.17 c | 101.74 ± 5.17 a | 164.60 ± 6.48 b |
GST (µM/g.tissue/min) | 5.08 ± 0.10 c | 3.11 ± 0.02 a | 3.96 ± 0.08 b |
MDA (nM/g.tissue) |
1.12 ± 0.04 a | 3.24 ± 0.07 c | 1.53 ± 0.09 b |
NO (µM/g.tissue) |
267.20 ± 8.08 a | 418 ± 7.87 c | 336.40 ± 12.78 b |
Catalase (U/min/g.tissue) | 506.81 ± 21.5 c | 226.88 ± 12.82 a | 369.33 ± 6.69 b |
Values are Mean ± SEM and values with different superscript letters are significantly different (p < 0.05)