Figure 6.

Overview of next‐generation vesicle formulations for DDS. Comparing EVs and liposomes on various aspects (no. 1–5), shows that they have inherent advantages and disadvantages. The generation of EV‐inspired liposomes or EV/liposome hybrid vesicles could be key to improving lipid vesicles as a DDS as they could incorporate the beneficial aspects of both EVs and liposomes. Another alternative for the generation of vesicles of biological origin, is to use the cellular membranes in a cell shearing approach.