Figure 1.

Stiffness of various 3D hydrogel models compared to ex vivo tumor tissue. Atomic force microscopy (AFM) measurements of the stiffness of Matrigel (100%), collagen I (2 and 6 mg mL⁻¹) and ex vivo colorectal tumor tissue. The inset is a zoom of the hydrogels’ stiffness. 3D hydrogel models were measured as n = 3 samples, with >30 measurement points per sample. One colorectal tumor tissue was collected and AFM measurements were conducted on three sections with >10 measurement points per section.