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. 2023 Sep 21;12(31):2302046. doi: 10.1002/adhm.202302046

Figure 5.

Figure 5

Tumor targeting ability of liposomes. A) Quantification of intracellular uptake after incubated with free IR780 and IR780‐LP in 4T1 cells in vitro (n = 3). B) Histogram of intracellular uptake of free IR780 and IR780‐LP by 4T1 cells after 4 h after incubation in vitro. C) Fluorescent images of cells treated with free IR780 and IR780‐LP 4 h after i.v. incubation. D) IVIS images of free IR780 and IR780‐LP distribution in 4T1 tumor‐bearing mice. E) Normalized fluorescence intensity of the tumor and major organs (n = 4). F) IVIS images of free IR780 and IR780‐LPs in hearts (H), livers (Li), spleens (S), lungs (Lu), kidneys (K), and tumors (T) at 48 h postinjection (n = 4, results were shown in mean ± S.D., *, p < 0.05, **, p < 0.01, ***, p < 0.001, ****, p < 0.0001).