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miR‐21 and AM21 gene regulation in human cancer cells. A) miR‐21 downstream gene signaling. KB and A549 cells were treated with AM21 at 200 nm for 4 h followed by replacement with fresh complete media and incubation for overnight. AM21 regulated miR‐21 downstream genes in free solution and lipofectamine in B) KB cells, in QTsome Original and QTPlus‐AM21 in C) A549 cells (n = 3).
