Figure 10.

Porin‐blocking experiment on porin‐containing (E. coli BL21 DE3 OMV) and porin‐deficient (E. coli BL21 DE3 OMV) membrane model. A) Permeation‐time course of norfloxacin in presence and absence of spermine. B) Apparent permeability coefficients (P _app) of norfloxacin in presence and absence of spermine. Points and columns represent mean ± SD. N = 12 from three independent experiments. A two‐way ANOVA was performed with Tukey's multiple comparisons post‐hoc test. **P < 0.002, ****P < 0.0001