Figure 11.

Apparent permeability coefficients (P _app) of eleven antibiotics on four vesicle‐derived membrane models. Antibiotics with expected porin‐facilitated pathway^{[ 32} , ⁶³ , ⁶⁴ , ⁶⁵ , ⁶⁶ , ^{67 ]} are depicted in blue, while antibiotics with predominantly porin‐independent pathways are depicted in orange.^{[ 7} , ¹⁵ , ⁶⁸ , ⁶⁹ , ^{70 ]} Antibiotics with various pathways are light brown columns.^{[ 32} , ⁶⁷ , ⁷⁰ , ^{71 ]} Columns represent mean + SD. N ≥ 9 from at least 3 independent experiments. A two‐way ANOVA was performed with Tukey's multiple comparisons post‐hoc analysis (Section S2, Supporting Information).