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In the tri‐culture, HepG2 islands (white circles) are surrounded by the vascular network (A,B). After printing HepG2 cells (C), they proliferate strongly between day 0 (D1) and 14 (D2), forming spheroidal agglomerations inside the agarose matrix with no intent of growing outside (E). Albumin synthesis increases during the first 11 days and is higher when the model is supported by a µVN (F), with * for p < 0.05 and ** for p < 0.01.
