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. 2022 Dec 12;12(7):2202751. doi: 10.1002/adhm.202202751

Figure 6.

Figure 6

Exosome mimetics promote angiogenesis in vivo through HIF‐1α/VEGFA pathway. A,B) The expression of CD31 in the DA@iPS‐EC NV group was significantly higher than that in the other groups (**p < 0.01). A,C) The expression of α‐SMA in the DA@iPS‐EC NV group was significantly higher than that in the other groups (**p < 0.01). D) Western blot assay showed that the expressions of HIF‐1α and VEGFA were significantly upregulated in the high glucose+DA group when compared with the high glucose group (**p < 0.01). F,E) Immunohistochemical staining showed that the highest HIF‐1α expression level was observed in the DA@iPS‐EC NV group (**p < 0.01). F,G) Immunohistochemical staining showed that the highest VEGFA expression level was observed in the DA@iPS‐EC NV group (**p < 0.01, *p < 0.05).