Figure 3.

Comparative clonal complex distribution in the respective MenB strain pools.

The seven most prevalent CCs identified in the Pfizer MenB Collection (2000–2006) are shown in the upper panel. The prevalence of these CCs among all MenB disease isolates from the contemporary PubMLST dataset (2007–2021) are shown in the lower panel. Highly represented (n > 100) FHbp variants within each CC are shown with a non-gray color; less frequently expressed variants are categorized as “other” and shown in gray. Nomenclatures for each variant are shown in Supplementary Table S1. CC = clonal complex; FHbp = factor H binding protein; MenB = meningococcal serogroup B.