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. 2024 Oct 11;19(10):e0310547. doi: 10.1371/journal.pone.0310547

Fig 1. Family genogram of FH and the Sanger sequencing map.

Fig 1

a) Family genogram of FH. The proband (II2) and younger brother (II7) carrying compound heterozygotes; black and grey indicate c.G1027A (p.G343S) and c.G1879A (p.A627T) mutation in LDLR gene, respectively. b) and c) The symptoms of xanthomas on the eyelid skin of the proband (b) and brother (c). d) The Sanger sequencing map of the c.G1027A (p.G343S) mutant and e) The corresponding wild-type Sanger sequencing map. f) The Sanger sequencing map of the c.G1879A (p.A627T) mutant and g) The corresponding wild-type Sanger sequencing map.