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. 2024 Oct 10;10(11):e1716. doi: 10.1097/TXD.0000000000001716

TABLE 5.

Independent predictors of early major complications, n = 2379

Univariate logistic regression analysis
(95% CI); P value
Multivariable logistic regression analysis
(95% CI); P valuea
Risk factors of major complications*
 Sex (male vs female) 1.00 (0.57-1.73); 0.99 1.11 (0.62-1.93); 0.73
 Donor age 1.04 (1.01-1.07); 0.002 1.04 (1.01-1.07); 0.005
 BMI
  20.0–24.9 kg/m2 Ref Ref
  <20 kg/m2 2.19 (0.80-5.17); P = 0.09 2.40 (0.86-5.77); 0.07
  25–29.9 kg/m2 0.88 (0.47-1.63); 0.69 0.81 (0.43-1.51); 0.51
  ≥30 1.09 (0.43-2.44); 0.84 1.01 (0.39-2.27); 0.99
 Site of nephrectomy, left vs right 0.99 (0.54-1.83); 0.98
 Year of donation
  1998-2008 Ref Ref
  2009-2018 1.32 (0.74-2.39); 0.36 0.99 (0.55-1.83); 0.98
  2019-2022 0.92 (0.36-2.11); 0.85 0.63 (0.23-1.53); 0.34
 Surgical method
  Laparoscopic transabdominal Ref Ref
  Laparoscopic retroperitoneal 2.42 (1.39-4.31); 0.002 2.13 (1.21-3.82); 0.01
  Open nephrectomy 0.51 (0.15-1.35); 0.22 0.50 (0.14-1.34); 0.21

aThe last column represents the entire multivariable model.

Multivariable logistic regression analysis was performed to analyze the independent risk factors for major early complications*, defined as Dindo-Clavien classification ≥3a (n = 56 donors).To account for the long observation time and potential procedural changes, the years of transplantations were forced into the model as a potential confounder. Thus, the point effects of the multivariable model must be interpreted with caution. The C-statistic of the full model was 0.677.

BMI, body mass index; CI, confidence interval.