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. 2024 Oct 11;14:23838. doi: 10.1038/s41598-024-75635-3

Table 6.

Significantly altered metabolite ratios based on the conducted weighted correlation network analysis.

Ratio p value non-CVD – SAP p value STEMI – non-CVD p value STEMI – SAP p value Kruskal
Anthranilic acid: Aspartic acid < 0.001 < 0.00001 < 0.001 < 0.00001
Anthranilic acid: Kynurenine < 0.00001 < 0.00001 < 0.00001
Anthranilic acid: Methionine < 0.001 < 0.001 < 0.0001
3OH Anthranilic acid: Tryptophol < 0.00001 < 0.00001 < 0.00001
Biopterin: Methionine sulfoxide < 0.00001 < 0.00001 < 0.00001
Biopterin: Metanephrine < 0.01 < 0.01 < 0.01
Aspartic acid: Biopterin < 0.001 < 0.001 < 0.0001
GSG (Glu: Ser + Gly) < 0.01 < 0.00001 < 0.0001 < 0.00001
Hydroxystearoylcarnitine (C18-OH): Indole-3-propionic acid < 0.0001 < 0.01 < 0.0001
Tryptophan:5OH Tryptophan < 0.0001 < 0.0001 < 0.00001
Citrulline: Ornithine < 0.01 < 0.01
Lauroylcarnitine (C12):Hydroxytetra-decanoylcarnitine (C14-OH) < 0.001 < 0.01 < 0.01
ADMA: NNMA < 0.0001 < 0.001
ADMA: Proline < 0.05 < 0.05
Arginine: ADMA < 0.001 < 0.01
Kynurenine: Tryptophan < 0.01 < 0.05 < 0.001
NMMA: Indole-3-carboxaldehyde < 0.05 < 0.001 < 0.001
3OH Kynurenine: Kynurenine < 0.01 < 0.01
Norepinephrine: Metanephrine < 0.01 < 0.01
Asparagine: Histidine < 0.01 < 0.05
Fischer (Leu + Ile + Val): (Tyr + Phe) < 0.01 < 0.05
Aspartic acid Methionine < 0.01 < 0.05
n = 22 n = 7 n = 13 n = 17