Table 5.

Concentrations of inflammatory markers before and after treatment in patients with CC

Marker	XELOX		XELOX + FZSBD
	Pre-treatment	Post-treatment	Pre-treatment	Post-treatment
CRP (mg/L)	18.25 ± 4.79	14.53 ± 5.23**	18.54 ± 5.02	10.23 ± 4.25***,#
IL-6 (pg/mL)	5.62 ± 2.18	4.02 ± 2.47*	5.81 ± 2.35	4.95 ± 2.23
TNF-α (pg/mL)	25.11 ± 6.59	22.75 ± 6.97	24.92 ± 6.70	17.45 ± 6.38***,#
IL-1β (pg/mL)	12.34 ± 3.27	7.40 ± 3.58***	12.57 ± 3.43	6.75 ± 3.15***

Notes: n = 23 each group. Data are shown as mean ± SD. The Student’s t-test and Tukey’s test were applied for the comparison between groups.

^*** P<0.001 vs. the pre-treatment group;

^** P<0.01 vs. the pre-treatment group;

^* P<0.05 vs. the pre-treatment group;

^# P<0.05 vs. the post-treatment group of XELOX.

CRP, C-reactive protein; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; IL-1β, interleukin-1β.