Table 4.
Causal effects of serum vitamin C levels on depressive risk estimated by MR
| Exposure/Outcome | nSNP | IVW | MR Egger | Weighted median | Weighted mode | Simple mode | Heterogeneity P | Pleiotropy P | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| OR (95% Cl) | P | OR (95% Cl) | P | OR (95% Cl) | P | OR (95% Cl) | P | OR (95% Cl) | P | IVW | MR Egger | |||
| Serum vitamin C levels/Depression | 11 | 1.21 (0.93-1.57) | 0.154 | 1.41 (0.82-2.43) | 0.247 | 1.37 (1.01-1.86) | 0.044 | 1.59 (1.09-2.31) | 0.035 | 1.61 (1.00-2.57) | 0.077 | 0.102 | 0.084 | 0.539 |
Abbreviations: IVW, inverse variance weighted; MR, Mendelian randomization; SNP, Single nucleotide polymorphisms.