Table 1.

Main active ingredients of traditional Chinese medicine wet compress in the treatment of soft tissue injury

Active ingredient of Chinese medicine	MOL number	Chinese medicine ingredient	The active ingredient corresponds to the target
Sitogluside	MOL000357	Zingiber, Safflower, Two-toothed achyranthes root	PGR, PTGS1, CHRM3, KCNH2, CHRM1, SCN5A, PTGS2, HTR3A, RXRA, ADRB2, NCOA2
Beta-sitosterol	MOL000358	Zingiber, Safflower, Two-toothed achyranthes root	PGR, NCOA2, PTGS1
			PTGS2, KCNH2, CHRM3, CHRM1, SCN5A, ADRA1A, CHRM2, ADRB2, SLC6A4, OPRM1, GABRA1, BCL2, BAX, CASP9, CASP3, CASP8
			PRKCA, PON1, MAP2
Kaempferol	MOL000422	Safflower, Two-toothed achyranthes root, Garden balsam stem	NOS2, PTGS1, AR, PTGS2, NCOA2, PGR, CHRM1, ACHE, SLC6A2, CHRM2, GABRA1, F7, RELA, IKBKB
			AKT1, BCL2, BAX, TNF, CASP3, MAPK8, XDH, MMP1, STAT1, PPARG, HMOX1, CYP3A4, CYP1A2, CYP1A1, ICAM1, SELE, VCAM1, NR1I2, CYP1B1, HAS2, GSTP1, AHR, SLC2A4, NR1I3, INSR, GSTM1, SLPI
Quercetin	MOL000098	Safflower, Two-toothed achyranthes root, Garden balsam stem	PTGS1, AR, PTGS2, NCOA2, KCNH2, SCN5A, ADRB2, MMP3, F7, RXRA, ACHE, GABRA1, RELA, EGFR, AKT1, VEGFA, CCND1, BCL2, BCL2L1, CDKN1A, EIF6, BAX, CASP9, PLAU, MMP2, MMP9, MAPK1, IL10, EGF, RB1, TNF, IL6, CASP3, TP53, ELK1, NFKBIA, POR, ODC1, XDH, CASP8, TOP1, RAF1, PRKCA, MMP1, HIF1A, STAT1, RUNX1T1, ERBB2, PPARG, ACACA, HMOX1, CYP3A4, CYP1A2, CAV1, MYC, F3, GJA1, CYP1A1, ICAM1, IL1B, CCL2, SELE, VCAM1, PTGER3, CXCL8, PRKCB, BIRC5, DUOX2, NOS3, HSPB1, IL2, NR1I2, CYP1B1, CCNB1, PLAT, THBD, SERPINE1, IFNG, IL1A, MPO, TOP2A, NCF1, HAS2, GSTP1, NFE2L2, AHR, SLC2A4, CXCL11, CXCL2, NR1I3, CHEK2, INSR, CLDN4, PPARA, PPARD, CRP, CXCL10, CHUK, SPP1, RUNX2, E2F1, E2F2, ACP3, CTSD, IGFBP3, IGF2, CD40LG, IRF1, ERBB3, PON1, NKX3-1, RASA1, GSTM1
Rutin	MOL000415	Safflower, Two-toothed achyranthes root, Garden balsam stem	RELA, TNF, IL6, CASP3, POR, CAT, IL1B, CXCL8, PRKCB, HMGCR, HAS2, GSTP1, INS, FCER2, ITGB2, TBXA2R