Table 4.
Results of mediation effects analysis in the range of BMI≤24kg/m2
| variables | Model 1a | Model 2b | Model 3c | |||
|---|---|---|---|---|---|---|
| Percentage of mediation effect | P value | Percentage of mediation effect | P value | Percentage of mediation effect | P value | |
| All-cause death | ||||||
| TG |
3.9 (0.7,0.84) |
0.1201 |
2.9 (0.3,23.5) |
0.1889 |
3.6 (1.0,12.2) |
0.0599* |
| TC |
3.4 (0.7,14.5) |
0.0922* |
2.9 (0.5,15.4) |
0.1250 |
2.3 (0.3,14.2) |
0.1473 |
| HDL-C | - | - | - | - | - | - |
| LDL-C |
1.1 (0.0,39.0) |
0.3120 | - | - |
1.1 (0.0,21.4) |
0.2672 |
| Apo-AI |
1.4 (0.0,81.2) |
0.3647 |
3.1 (0.2,34.4) |
0.2367 |
1.1 (0.0,68.7) |
0.3521 |
| Apo-B | - | - | - | - | - | - |
| CV death | ||||||
| TG |
3.5 (0.4,25.0) |
0.1794 |
3.3 (0.3,27.1) |
0.1995 |
3.8 (0.9,15.5) |
0.0922* |
| TC |
2.9 (0.4,17.1) |
0.1471 |
2.9 (0.4,18.3) |
0.1559 |
2.6 (0.3,18.1) |
0.1645 |
| HDL-C | - | - | - | - | - | - |
| LDL-C | - | - | - | - |
1.1 (0.0,35.4) |
0.3061 |
| Apo-AI |
1.4 (0.0,95.0) |
0.3929 |
3.9 (0.3,36.1) |
0.2230 |
3.1 (0.2,29.5) |
0.2142 |
| Apo-B | - | - | - | - | - | - |
| MACCEs | ||||||
| TG |
5.0 (1.1,20.2) |
0.0867* |
3.7 (0.5,23.2) |
0.1556 |
4.4 (1.2,14.5) |
0.0535* |
| TC |
4.8 (1.4,15.1) |
0.0407* |
4.4 (1.2,15.1) |
0.0527* |
4.4 (1.1,16.3) |
0.0650* |
| HDL-C | - | - | - | - | - | - |
| LDL-C |
4.0 (1.0,14.6) |
0.0598* |
3.3 (0.7,14.7) |
0.0931* |
4.4 (1.1,16.1) |
0.0621* |
| Apo-AI | - | - |
1.9 (0.1,22.9) |
0.2311 | - | - |
| Apo-B |
4.3 (1.0,17.2) |
0.0804* |
3.1 (0.4,19.0) |
0.1480 |
4.8 (1.2,16.9) |
0.0609* |
*p<0.1
aModel 1 unadjusted
bModel 2 adjusted for age, sex
cModel 3 adjusted for age, sex, LVEF hypertension, DM eGFR, CRP