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. 2024 Aug 22;25(5):855–873. doi: 10.1007/s11154-024-09898-6

Table 5.

Epidemiology of ACTH deficit and other pituitary hormones deficit in craniopharyngiomas

Authors (Reference) Num of patients Age at diagnosis
mean (ranges)
Gender
M/F (%)
Timing of pituitary
function evaluation
Frequency of pituitary hormones deficit
ACTH-
deficit
TSH-
deficit
FSH/LH-
deficit
GH-
deficit
AVP-
deficit
Abalı et al. [69] 29 8.7 (0.7–16.9) M: 62% F: 38% N.A. 93.1% 96.5% 51.7% N.A. 89.6%
Sončka Jazbinšek et al. [70] 46

19 childhood-onset

(< 18 yrs, mean age 10,6)

N.A. N.A. 94.7% 94.7% 84.2% 94.7% 78.9%

27 adult-onset

(> 18, mean age 52)

N.A. N.A. 74.1% 81.5% 70.4% 51.8% 70.4%
Cavalcanti Tosta-Hernandez et al. [71] 57 9.6 M: 61.4% F: 38.8% N.A. 91.2% 93% 52.6% 96.5% 80.7%
Miao et al. [67] 200 8.1 M: 65% F: 35% Before surgery 28.8% 16.3% N.A. N.A. 11.8%
After surgery 56.2% 70.3% N.A. N.A. 85.5%
Capatina et al. [72] 107 35 childhood-onset M: 45.7% F: 54.3% N.A. 82.8% 85.7% N.A. 74.2% 68.2%
72 adult-onset M: 61.1% F: 38.9% N.A. 75% 75% N.A. 73.6% 34.3%
Van Santen et al. [73] 112 25 yrs M: 51% F: 49% N.A. 85% 96% 91% 94% 68%
Wijnen et al. [74] 178 47 yrs M: 49.4% F: 50.6% N.A. 81.5% 91.6% 87.1% 83.1% 62.3%

N.A. data not available, M male, F female, ACTH AdrenoCorticoTropic Hormone, TSH Thyroid-Stimulating Hormone, FSH Follicle-Stimulating Hormone, LH Luteinizing Hormone, Yrs years, AVP Arginine VasoPressin, GH Growth Hormone