Table 3.

Statistical comparisons of patients’ clinical scores between baseline (T0) and follow-up (T1). Patients were divided into two groups based on the caregivers' CBI score or according to the family relationship with caregivers

Clinical assessment	Baseline		p-value	Follow up		p-value
	Caregivers CBI < 24	Caregivers CBI ≥ 24		Caregivers CBI < 24	Caregivers CBI ≥ 24
MoCA	23.5 (20.5–25.7)	23.5 (18.5–26.5)	0.534	25.0 (21.0–28.0)	25.0 (22.7–28.0)	0.457
HRS-A	8.0 (3.0–14.7)	14.0 (11.5–20.5)	0.034*	6.0 (3.2–8.0)	11.0 (4.0–14.5)	0.255
HRS-D	12.5 (7.2–14.0)	7.0 (5.2–9.0)	0.383	12.5 (6.5–16.2)	9.5 (3.0–12.2)	0.069
	Partner	Son/Daughter		Partner	Son/Daughter
MoCA	24.0 (21.0–26.0)	19.0 (14.5–27.0)	0.216	25.0 (22.5–28.0)	21.0 (17.5–27.5)	0.133
HRS-A	10.0 (4.0–18.0)	12.0 (6.0–16.0)	0.662	7.0 (3.5–11.5)	6.0 (4.5–10.5)	0.222
HRS-D	12.0 (6.5–14.5)	13.0 (8.0–16.5)	0.422	8.0 (5.5–12.0)	7.0 (4.0–8.0)	0.451

Significant differences are * < 0.05; ** < 0.01; *** < 0.001

Montreal Cognitive Assessment (MoCA); Hamilton Rating Scale—Anxiety (HRS-A); Hamilton Rating Scale—Depression (HRS-D)