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. 2024 Oct 12;3:142. doi: 10.1038/s44172-024-00285-2

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© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024

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Fig. 1 — Including the microfluidic chamber (a–f) and the system-level housing (g–h). a Expanded view of a full chamber, with all components labeled. b Closed chamber with a closeup view of the tissue and PDMS clamped between two chamber halves. c Tissue explant before and after the experiment. d, e The actual manufactured chamber assembled (front and back, respectively). f Flow simulation through the chamber’s microfluidics. g Expanded view of the microphysiological system. h The manufactured and fully assembled system with three chambers connected the system.